Metastatic carcinoma of unknown primary (CUP) has a very poor prognosis, and no standard first-line therapy currently exists.Here, we report the results of a phase II study utilizing a combination of gemcitabine and irinotecan as first-line therapy.Treatment was with gemcitabine 1000 mg/m(2) and irinotecan 75 mg/m(2) weekly times four on a six week

Aiming at the current situation of lack of environment and equipment in radar training, a radar operation training Crash Bandicoot Pins method based on the combination of virtual and real is proposed.Firstly, the connotation of the concept of virtual-real combination is analyzed.Secondly, the interaction methods of combining physical radar and virt

This article examines hate speech and conspiracy theories against LGBTQI+ people in the Spanish Twittersphere, on the occasion of the celebration of International LGBTQI+ Pride Day and the debates before the entry into force of the Trans Law.A dataset of 410,015 organic tweets in Spanish between 2020 and 2022 was collected using Crash Bandicoot Pin

Diverse environmental gradients in Central Asia and Mongolia, from high mountain forests to semi-desert lowlands salinized by past agriculture and water withdrawals, pose challenges to restoring Glasreinigungsmaschine degraded forests and landscapes.Technical approaches in dryland forestry and agroforestry methods are available to overcome these ch

Ashley Lamb,1 Brandon McKinney,1 Petros Frousiakis,1 Graal Diaz,2 Stephan Sweet1 1Orthopedic Surgery, Bookcase Community Memorial Hospital, Ventura, CA, USA; 2Research Department-Graduate Medical Education, Community Memorial Healthcare System, Ventura, CA, USACorrespondence: Graal Diaz, Research Department-Graduate Medical Education, Community Mem